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Human Brain Mapping

Dexamphetamine and the resting-state electroencephalogram

What a single dose of dexamphetamine does to resting EEG and to the connectivity between regions.

System outline
  1. 01Dexamphetamine
  2. 02Resting EEG
  3. 03Functional connectivity

The idea

Dexamphetamine is a stimulant with a long history in attention research. This paper measures what it does when a person is not performing a task: the resting electroencephalogram, and the functional connectivity between cortical regions.

The approach

Resting EEG is recorded with and without dexamphetamine. The analysis covers both the spectrum of the signal and the coupling between sites, so a change in power and a change in connectivity can be told apart.

  • A stimulant dose, at rest
  • EEG power and connectivity measured separately
  • A psychopharmacology result, not a task-performance result
  • Albrecht, Roberts, Price, Lee, Iyyalol, Martin-Iverson
  • Human Brain Mapping, 37(2), 570–588

The paper: pmc.ncbi.nlm.nih.gov .