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Interactive neuroscience

Dorsal Anterior Cingulate

Four hundred neurons of dorsal anterior cingulate cortex, Brodmann area 24, on a Stroop task with a conflict bar and a theta trace.

Dorsal anterior cingulate simulation with purple, blue and green cells, a Stroop word and a theta trace.
Dorsal anterior cingulate: the layered population, the Stroop word and the theta trace.

The idea

The title line reads DORSAL ANTERIOR CINGULATE, and the subtitle reads Brodmann Area 24 · Medial Prefrontal Cortex. The page treats this cortex as agranular, so the stack has no layer IV. A Stroop trial supplies the conflict: a colour word whose ink may or may not match the word. The conflict number is the mean activity of the von Economo cells.

The approach

The legend names three populations. Von Economo neurons are purple spindles. Pyramidal cells are blue. Interneurons are green and smaller. The 400 cells sit in four bands: layer I has 20, layer II/III has 120, layer V has 180, and layer VI has 80. A cell in layer V is drawn as a von Economo neuron with probability 0.25. In layers II/III and VI that probability is 0.05. Layer I has none. A further fifth of every layer is drawn as interneurons. The HUD counts the von Economo cells that draw produced, next to neurons, active cells and firing rate. While conflict is high, the purple cells shift towards red.

On the left, Stroop Task shows RED, GREEN or BLUE, painted in red, green or blue ink. The line under the word reads Congruent in green or Incongruent in red. The keys are R, G and B, and a correct press is the ink. An incongruent trial stimulates both the word and the ink and raises conflict. A wrong key, or two seconds without an answer, injects an error and the view flashes. Between trials the word collapses to a dim dot, and the type line returns to a dash. At rest the box reads READY.

Conflict Signal, top right, is a number and a bar that runs from blue to red. Above 0.25 the number turns amber. Above 0.5 it turns red. High Conflict forces an incongruent trial while a task is running, and otherwise injects a conflict signal of strength 1.2. Force Error drives the error input on its own.

The trace labelled Theta Power (4-8 Hz) is 150 samples long. The oscillator steps at 6 Hz. Its amplitude is the power, which starts at 0.3 and rises with conflict and with errors. The line is indigo, amber once power passes 0.4, and red once it passes 0.6. Under it the page prints that power. Trials, accuracy, and separate congruent and incongruent reaction times, in milliseconds, sit along the bottom. Auto Camera starts on.

  • Layers I, II/III, V and VI hold 20, 120, 180 and 80 cells; there is no layer IV
  • Von Economo cells are purple spindles, drawn with probability 0.25 in layer V
  • Stroop ink is red, green or blue; R, G and B answer the ink, not the word
  • Theta trace is labelled 4-8 Hz and stepped at 6 Hz; conflict above 0.5 turns the number red
Open the full demo

Play the current build: /simulations/dorsal-anterior-cingulate .